Nanopore Targeted and Whole-Genome Sequencing
Long-read sequencing of enriched or high-burden specimens for genotyping, single-nucleotide-polymorphism typing and reconstruction of transmission chains. Direct sequencing is constrained by the low proportion of bacillary DNA in clinical material.
- Technology
- Molecular (NAAT) · Next-generation sequencing
- What it measures
- M. leprae genome, for strain typing and resistance
- Developer
- Oxford Nanopore-based laboratory workflows
- Specimen
- Skin biopsy
- Development status
- RUO with analytical validation
- Regulatory status
- None / RUO
- Intended use
- Strain typing and reconstruction of transmission chains
- Main limitation
- Clinical samples contain little bacterial DNA, so enrichment is needed.
- Linked publications
- TPP-1, confirming leprosy
- 30.0 of 100, low alignment
Open this test in the landscapeAll 37 tests · Home