Leprosy Diagnostic Landscape

Circulating MicroRNA Signature

Quantification of circulating microRNA panels in serum or plasma, investigated for discriminating leprosy from clinical mimics and for predicting type 1 and type 2 reactions.

Technology
Host Response · Transcriptomics
What it measures
Serum or plasma miRNA panel
Developer
Academic groups, including the Instituto Lauro de Souza Lima and the Federal Universities of Minas Gerais and Pará (Brazil)
Specimen
Venous blood
Development status
Assay in development
Regulatory status
None / RUO
Intended use
Discrimination from clinical mimics and prediction of type 1 and type 2 reactions
Main limitation
Still at the discovery stage, with no validated assay format.
Linked publications
4
Collaborating institutions
Southern Medical University (Guangzhou, China), A.C. Camargo Cancer Center (São Paulo, Brazil)
TPP-1, confirming leprosy
20.0 of 100, low alignment
TPP-2, infection in contacts
12.5 of 100, low alignment
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