Leprosy Diagnostic Landscape

Environmental and Reservoir qPCR (Soil, Water, Armadillo and Squirrel)

Amplification of M. leprae and M. lepromatosis DNA from soil, water, and armadillo and squirrel tissues. It is applied to the investigation of zoonotic and environmental sources rather than to human diagnosis.

Technology
Molecular (NAAT) · Environmental surveillance
What it measures
M. leprae and M. lepromatosis DNA in non-human samples
Developer
Academic surveillance groups, including the National Hansen's Disease Program (USA), Leiden University Medical Center (the Netherlands) and the University of Edinburgh (UK)
Specimen
Environmental / animal
Development status
LDT with clinical validation
Regulatory status
None / RUO
Intended use
Investigation of zoonotic and environmental sources of M. leprae
Main limitation
Not a test for people, and recovery of DNA from soil, water and animals varies.
Linked publications
59
Collaborating institutions
Fiocruz (Brazil), Instituto Lauro de Souza Lima (Bauru, Brazil), ICMR-National JALMA Institute (Agra, India)
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