Dried Blood Spot Serology
Capillary blood is collected on filter paper, dried, transported at ambient temperature and eluted for antibody quantification by immunoassay or multiplex bead array. The method separates the point of collection from the point of analysis.
- Technology
- Serology (Antibody) · ELISA / multiplex bead
- What it measures
- Anti-PGL-I and anti-LID-1 antibodies eluted from filter paper
- Developer
- Academic groups and surveillance programmes
- Specimen
- Dried blood spot
- Development status
- LDT with clinical validation
- Regulatory status
- None / RUO
- Intended use
- Integrated serosurveillance where collection and analysis are geographically separated
- Main limitation
- Limited by what anti-PGL-I serology can detect, and results depend on a central laboratory.
- Linked publications
- 19
- TPP-1, confirming leprosy
- 61.0 of 100, partial alignment
- TPP-2, infection in contacts
- 62.0 of 100, partial alignment
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